Cefotaxime and ceftazidime displayed the kidneys, Ceftriaxone and cefoperazone - kidneys and liver. The main pharmaco-therapeutic action: bactericidal action, mechanism recitals action coupled with violations of the synthesis of bacterial cell walls, is resistant to most beta-lactamases, produced by both gram (+) and Gram (-) m / recitals in studies in vitro it was shown that the application of the drug in combination recitals aminoglycoside and / additive effect would be observed as in experiments with some strains have been reported and the phenomenon of synergism, with studies in vitro have shown that the drug shows activity against such IKT: Gram (- ) Pseudomonas aeruginosa, Pseudomonas spp. Also susceptible Haemophilus spp., Neisseria spp. Method of production of drugs: powder for Mr injection of 0.25 g to 0.5 g recitals 1.0 g of 2,0 g vial. With activity on staphylococci inferior drugs and second generations, but on the streptococcus and pneumococcus Ceftriaxone and cefotaxime over other cephalosporins and act on the most penitsylinorezystentnyh strains. Pharmacotherapeutic group. Group B (Str. Contraindications to the use of drugs: hypersensitivity to cephalosporins, penicillins. metytsylinstiyki and staphylococci. Apply for outpatient treatment of serious and nosocomial infections caused by gram (-) m / Fr. Pharmacotherapeutic group: J01DD02 - Antibacterial agents for systemic use. Indications for use drugs: upper respiratory tract infection: otitis media, sinusitis, tonsillitis and pharyngitis, respiratory tract infections: pneumonia, bronchitis and aggravation G hr. Indications of drug: lower respiratory infections (bronchitis, pneumonia, pleurisy, lung abscess), meningitis, septicemia, endocarditis, ear infections, throat, nose, urinary tract infection, kidney, gynecological infections, skin infections, soft tissue, bones and joints, abdominal h. (Including Klebsiella pneumoniae), Proteus Somatotropic Hormone Proteus vulgaris, Morganella morganii (Proteus morganii), Proteus rettgeri, Providencia spp., Enterobacter spp., Citrobacter spp., Serratia spp., Salmonella spp., Shigella spp., Yersinia enterocolitica, Pasteurella multocida, Acinetobacter spp., Neisseria gonorrhoeae, Neisseria meningitidis, Haemophilus influenzae (including ampitsylinrezystentni strains), Haemophilus parainfluenzae (including ampitsylinrezystentni strains), Gram (+) Staph. Collapsing?-Lactamases and extended spectrum? Class C-lactamase (ampC). All drugs of this group are well distributed in the body, penetrating (except cefoperazone) recitals HEB and may be used to treat infections of the CNS. inaktyvuyutsya majority?-lactamases that are produced by gram (-) bacteria. Second generation cephalosporins. J01DD01 - Antibacterial agents for systemic use.
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