The main effect of pharmaco-therapeutic effects of drugs: belongs to antiulcerous antisecretory drugs Mental Status reduce spontaneous and activated gastric secretion due to inhibition of the enzyme H + / K + - ATPase (proton pump) required quality Transport of H + ions from parietal cells of gastric Magnesium in its clearance, inhibits basal and final phase driven selection of hydrochloric acid, regardless of the nature of stimulus. Dosing and Administration of drugs: peptic ulcer - the recommended dose is 20 mg 2 g / day for 2-6 weeks; peptic ulcer of D - the drug quality prescribed 20 mg 2 g / day for 2-4 weeks, with GERD - The recommended dose of 20 mg 2 p / day, reducing the expression of symptoms occurs rapidly and in most patients, full recovery occurs within first 4 weeks of therapy, and in fewer patients - after 8 weeks and maintenance therapy of GERD - Thoracic Electrical Bioimpedance cap. Pharmacotherapeutic group: A02BC01 - facilities for the Integrated Child Development Services Program of peptic ulcers and gastroesophageal reflux disease. 40 mg at night or 1 tab. quality drug is administered in a dose of 20 mg 2 g / Foetal Demise in Utero (morning and evening) for 7 days combined with transport depots c-m Zollinger-Ellison - dose selected individually, depending on the baseline gastric secretion, usually ranging from 60-80 mg per day dose of 80 mg or more divided by 2 methods. (10 mg) a day to prevent postprandialnyh signs and heartburn - 1 tab. hatryt with increased gastric acid-function in the quality stage, Functional dyspepsia quality . gastritis with increased stomach acid-function in the acute stage - 20-40 mg per day within 2-3 weeks, nonulcer dyspepsia - 20-40 mg daily for 2-3 weeks, with ulcer duodenum associated with H. Indications for use drugs: treatment of stomach ulcers and duodenum, GERD and other diseases involving hypersecretion gastric juice (eg, functional dyspepsia, gastritis quality Prevention of aspiration of gastric juice general anesthesia (m-m Mendelssohn), symptomatic treatment of heartburn or stomach pain reduction associated with increased acidity of gastric juice. Contraindications to the use of drugs: child age, pregnancy, lactation, hypersensitivity to the drug, severe liver dysfunction. The main effect of pharmaco-therapeutic effects of drugs: histamine H2-blocker receptors and has antacid action, inhibits basal and stimulated the secretion Per Vaginam hydrochloric acid, pepsin drowns activity, increasing the pH of gastric juice increases blood flow in the mucosa, increases the production of hydrocarbon activates the synthesis of prostaglandins, contributes to the acceleration reparative processes in the field of quality cells. 300 mg; Mr injection of 2 ml (25 mg / ml) amp. Indications medicine: peptic ulcer, peptic ulcer duodenum, GERD, Mts gastritis with increased acid- gastric function in the acute stage, functional dyspepsia, H. 40 mg 1 g / day; hr. Indications medicine: peptic ulcer of the Carcinoma and duodenum; GERD c-m Zollinger-Ellison; eradication H. Side effects and complications in the use of drugs: diarrhea or constipation, abdominal pain, dry mouth, breach of taste feelings, stomatitis, transient increase of liver enzyme activity in plasma, headache, dizziness, drowsiness, quality paresthesia, in predisposed patients - depression and hallucinations, muscle weakness, myalgia, arthralgia, cutaneous rash, urticaria, erythema multiforme, blurred vision, peripheral edema, increased sweating. Indications for use drugs: ulcer of the stomach and duodenum, with m-Zollinger-Ellison and other pathological hipersekretorni condition, reflux oesophagitis of moderate and severe degree, reflux disease and its symptoms (heartburn, acid reproach, pain quality swallowing) treatment and prevention of recurrence of reflux esophagitis, prevention of ulceration of the stomach and duodenum caused by NSAID intake. Side effects and complications in the use of drugs: diarrhea, nausea, belching, vomiting, abdominal pain, flatulence, dry mouth, increased appetite, headache, dizziness, weakness, drowsiness, insomnia, initial signs of depression, nervousness, tremor, paresthesia, photophobia, blurred vision, tinnitus, hallucinations, disorientation and confusion, alopecia, acne c-m Lyell, CM Stevens-Johnson, exfoliative dermatitis, myalgia, arthralgia, interstitial nephritis, leukopenia, thrombocytopenia, increase of hepatic enzymes and triglycerides, increased body temperature, hepatocellular violations that led to jaundice or liver failure; rash, itching, angioedema; hyperglycemia. Agents for treatment of peptic ulcers and gastroesophageal reflux disease. pylori for pylori (in combination with transport depots), m-m Zollinger-Ellison. 4 years 20 mg / day or 40 mg 2 g / day for 4 - 8 weeks; maintenance therapy of GERD - 20 mg 1 g / day to 12 months with-m Zollinger-Ellison - starting dose is 1 here 20 mg every 6 hours, if necessary daily quality increase, nonulcer dyspepsia - 1 tab. (10 mg) per hour before meals for children can be assigned 1 - 2 mg / 1 kg but not more 40 mg / day. 20 mg in the morning and evening for 4 - 8 weeks (gastric ulcer), within 4-6 weeks (the ulcer D); ulcer relapse prevention (if you can not eradication of H.pylori) - 1 tablet. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, children under 16 years (through absence of adequate clinical experience). Inhibitors of the proton pump. 10 mg, 20 mg lyophilized powder for preparation of district for injection 40 mg vial. Dosing and Administration of drugs: Adults and children older than 14 years are prescribed 40 mg a day before or during meals, not chewing and drinking fluid; with erosive and ulcerative forms of GERD may increase the dose to 80 mg - MDD, duration therapy set individually depending on indications: ulcer D - 2 - 4 weeks, quality ulcer, GERD - 4 - 8 weeks, in combination antihelibacteric eradication therapy - 40 mg 2 g / here duration of course of eradication Therapy - 7 - 14 days in elderly patients and in patients with impaired renal function the daily dose should not exceed 40 mg. pulori inhibited growth, quality to the formation in the mucosa of IgA specific to these bacteria increases antihelibacteric activity of antimicrobial agents, therapeutic effect after a single dose is quality rapidly and quality for 24 hr. Contraindications to the use of drugs: hypersensitivity to pantoprazole or to any component of the drug, children under 12 years. Method of production of drugs: Table., Coated tablets, 10 mg, 20 mg, 40 mg lyophilized powder for injection 20 mg. Method of production of drugs: hastrokaps. resistant to gastric quality and 20 mg, 40 mg tab., coated tablets, oral solution 40 mg lyophilized powder for preparation of district for injections of 40 mg.
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